Induced connective tissue metabolism in vivo: reutilization of pre-existing collagen.

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Induced connective tissue metabolism in vivo: reutilization of pre-existing collagen.

Light and electron microscopy of resorbing connective tissues have shown that the collagen fibers and fibrils disappear. It is usually presumed that resorbed collagen is degraded proteolytically to hydroxyproline-containing peptides and to free amino acids, including hydroxyproline. We wish to present evidence that collagen can be resorbed and then reutilized without such breakdown. Urinary exc...

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ژورنال

عنوان ژورنال: Proceedings of the National Academy of Sciences

سال: 1966

ISSN: 0027-8424,1091-6490

DOI: 10.1073/pnas.56.1.277